Agilent Services

The Agilent CoE is packed with high-end equipment that serves as a shared resource which can allow anyone to dabble in quantitative biology, asking and answering questions from bioenergetics to cellular impedence, and from multi-omics to immunophenotyping, and everything in between. Listed below are the various equipment pieces and their distinguishing features.

Resources

XFPro Seahorse system

Detect discrete changes in cellular bioenergetics (all mitochondrial readouts) in real-time which provides a clear window into the critical functions driving cell signaling, proliferation, activation, toxicity, and biosynthesis.

xCELLigence RTCA eSight system

Cells constantly undergo changes in cell state (division, detachment, adhesion, migration); this instrument can help you keep your hand on the pulse of all of this and more and assess their health by combining Imaging (morphology) & Impedance (adhesion). This enables comprehensive insight into cell health, behavior, and function (e.g., strength of adhesion, changes in morphology, proliferation, and cytolysis) and cell biology processes using live, simultaneous, and real time biosensor impedance-based and image-based measurements. Check out all that is possible using multiparametric real-time automated readouts using simultaneous cellular impedance and live cell imaging.

1290 Infinity II Bio LC/TQ System

The new 6495D triple quadrupole LC/MS system is an ultrahigh-performance system built for research and testing labs investigating large batches of samples. Equipped with the latest, innovative iFunnel technology, this LC/MS/MS achieves ppq-level detection limits for the most challenging analytes in heavy matrix, for example in 'omics, food, and environmental analysis, while providing high precision at sub-millisecond dwell times. You can now accomplish 3 powerful goals: (i) Population Analysis of the Plasma Lipidome; (ii) End-to-End Targeted Metabolomics; (iii) Quantitative Proteomics Using Standard- or Nanoflow HPLC.

BioTek Cytation 10 Confocal Imaging Reader

BioTek Cytation C10 confocal imaging reader combines automated confocal and widefield microscopy with conventional multimode microplate reading. The patented confocal design gives exquisite resolution and optical sectioning capabilities for many sample types. A Hamamatsu scientific CMOS camera, Olympus objectives, and laser-based illumination deliver high-quality images.Cytation C10 also includes widefield fluorescence, brightfield and phase contrast optics. The variable bandwidth monochromator-based multimode plate reading is based on the proven design of the Agilent BioTek Synergy products. Environmental controls, 3D viewer, and Gen5 software enable high-quality results for many applications.

NovoCyte Penteon Flow Cytometer

The NovoCyte Penteon flow cytometer provides an expanded set of capabilities that accommodate today's high-end and increasingly sophisticated multi-color flow cytometry assays. You now have the flexibility to choose from up to 30 fluorescence channels utilizing up to 5 lasers with up to 30 independent detectors. The NovoSampler Q can be integrated into different laboratory automation platforms and efficiently processes both FACS tubes (using a 40-tube rack) and 24-, 48-, 96-, and 384-well plates. The intuitive and industry leading NovoExpress software has been further advanced, providing an exceptional user experience in data acquisition, analysis and reporting.

Dako Autostainer Link 48

With a streamlined profile and smaller footprint, Autostainer Link 48 allows you to standardize and improve throughput in the processing and staining of histopathology slides while minimizing the impact to valuable laboratory bench space.